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STING antibody

Anti-STING antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33549
Anti-STING antibody used in IHC (Paraffin sections) (IHC-P). GTX33549
Anti-STING antibody used in Western Blot (WB). GTX33549

Cat. No. GTX33549

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all MPYS products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

42 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 170-379 of human TMEM173 (NP_938023.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transmembrane protein 173 , ERIS , MITA , MPYS , NET23 , SAVI , STING , STING-beta , hMITA , hSTING

Cellular Localization

Endoplasmic reticulum membrane,Mitochondrion outer membrane,Cell membrane,Cytoplasm

Background

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Database

Research Area

DATA IMAGES

Anti-STING antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33549

GTX33549 ICC/IF Image

ICC/IF analysis of L929 cells using GTX33549 STING antibody.
Blue : DAPI
Dilution : 1:100

Anti-STING antibody used in IHC (Paraffin sections) (IHC-P). GTX33549

GTX33549 IHC-P Image

IHC-P analysis of rat pancreas tissue using GTX33549 STING antibody.
Dilution : 1:100

Anti-STING antibody used in Western Blot (WB). GTX33549

GTX33549 WB Image

WB analysis of various sample lysates using GTX33549 STING antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

Application Reference

Xiaofeng G et al. CNS Neurosci Ther 2023; 29 (4) : 1178-1191 PERK-STING-RIPK3 pathway facilitates cognitive impairment by inducing neuronal necroptosis in sepsis-associated encephalopathy.
Application : WB
Reactivity : Mouse
Submit a Reference

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399