*Optimal dilutions/concentrations should be determined by the researcher.
Human Cerebellum shows cytoplasm staining in purkinje cells.
Not tested in other applications.
The peptide used to generate this antibody is available for purchase (GTX89739-PEP).
This antibody is expected to recognise both reported Human isoforms (NP_055641.3 and NP_003598.2).
Mouse, Rat, Bovine, Dog(>80% identity)
TBS pH7.3, 0.5% BSA
0.02% Sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Peptide with sequence SGEVRLRQLEQFI-C, from the N Terminus of the protein sequence according to NP_055641.3; NP_003598.2.
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
CDC42 binding protein kinase alpha , MRCK , MRCKA , PK428
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2018]