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MRP6 antibody [M6II-31]

Anti-MRP6 antibody [M6II-31] used in Immunohistochemistry (IHC). GTX23381

Cat No. GTX23381

Host

Rat

Clonality

Monoclonal

Clone Name

M6II-31

Isotype

IgG2a

Application

WB, ICC/IF, IHC-P, IHC-Fr, IHC

Reactivity

Human
Package
250 μl ($319)

APPLICATION

Application Note

Western blotting: use at a dilution of 1/20 to 1/50. FACS: assay dependent. Immunocytochemistry: use at a dilution of 1/20 - 1/50 on acetone fixed cell preparations. Immunohistochemistry: use at a dilution of 1/20 - 1/50 on frozen and formaldehyde-fixed paraffin-embedded tissuesections. Optimal dilutions / concentrations should be determined by the end user. For optimal staining in IHC, the sections should be pretreated with an antigen unmaskingsolution, for example a sodium citrate based buffer. The primary antibodyshould be incubated for about 60 minutes at room temperature when performing IHC.

Calculated MW

165 kDa. ( Note )

Positive Control

Liver, kidney and cell Lines (drug-sensitive parental cell lines and their multidrug-resistant derivatives).

Product Note

This antibody detects with MRP 6. This antibody does not cross-react with MDR 1,MRP 1, MRP 2 or MRP 3, MRP 4 & MRP 5.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant with 0.1% sodium azide and 1% BSA

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Bacterial fusion protein of human MRP 6, containing amino acids 764-964, spanning the putative 12th transmembrane region as well as predicted internal and external regions of the protein.

Purification

Tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ATP binding cassette subfamily C member 6 , ABC34 , ARA , EST349056 , GACI2 , MLP1 , MOAT-E , MOATE , MRP6 , PXE , PXE1 , URG7

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MRP6 antibody [M6II-31] used in Immunohistochemistry (IHC). GTX23381

GTX23381 IHC Image

MRP 6 Immunohistochemistry

REFERENCE

There are currently no references for MRP6 antibody [M6II-31] (GTX23381). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for MRP6 antibody [M6II-31] (GTX23381). Be the first to share your experience with this product.
SDS
Sodium Azide.pdf
Package List Price ($)
$ 319