GeneTex
United States (US)

MRPL11 antibody

MRPL11-antibody-GTX87823-IHC-1_18121411_493.jpg
MRPL11-antibody-GTX87823-ICC_IF-1_18121411_949.jpg
MRPL11-antibody-GTX87823-WB-1_18121411_383.jpg

Cat No. GTX87823

Host Rabbit
Clonality Polyclonal
Application WB, ICC/IF, IHC-P, ELISA
Reactivity Human, Monkey
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

20 kDa. ( Note )

Specificity/Sensitivity

MRPL11 Antibody detects endogenous levels of total MRPL11 protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human MRPL11.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

L11mt, MRP-L11, MRPL11, 39S ribosomal protein L11, mitochondrial, MRP L11

Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q. [provided by RefSeq]
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Database

Research Area

DATA IMAGES
MRPL11-antibody-GTX87823-IHC-1_18121411_493.jpg

GTX87823 IHC-P Image

Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue, using MRPL11 Antibody. The picture on the right is treated with the synthesized peptide.

MRPL11-antibody-GTX87823-ICC_IF-1_18121411_949.jpg

GTX87823 ICC/IF Image

Immunofluorescence analysis of A549 cells, using MRPL11 Antibody. The picture on the right is treated with the synthesized peptide.

MRPL11-antibody-GTX87823-WB-1_18121411_383.jpg

GTX87823 WB Image

Western blot analysis of extracts from COS cells, using MRPL11 Antibody. The lane on the right is treated with the synthesized peptide.