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MSH2 antibody

Cat No. GTX16833

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, IHC-Fr, IP, IHC (Formalin)

Reactivity

Human, Mouse
Package
50 μg ($379)

APPLICATION

Application Note

For IHC-Fr: Use at a concentration of 2 μg/ml. For IHC-P and IP: Use at an assay dependent dilution. For WB: Use at a concentration of 1 - 1.5 μg/ml. Predicted molecular weight: 100 kDa. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

105 kDa. ( Note )

Positive Control

HCT116 OR SW480 cells

PROPERTIES

Form

Liquid

Buffer

50% Glycerol, 50mM Sodium Phosphate

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length recombinant MSH2 protein.

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

mutS homolog 2 , COCA1 , FCC1 , HNPCC , HNPCC1 , LCFS2 , hMSH2

Cellular Localization

Nucleus

Background

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Database

Research Area

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Package List Price ($)
$ 379