GeneTex
United States (US)

MSH2 antibody

GTX54377_20180530_WB_18121411_343.jpg
GTX54377_20180530_IP_18121411_928.jpg

Cat No. GTX54377

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IP
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IP Assay dependent
Not tested in other applications.

Calculated MW

105 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 1-300 of human MSH2 (NP_000242.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

LCFS2 Antibody , FCC1 Antibody , HNPCC1 Antibody , COCA1 Antibody , HNPCC Antibody

Background

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Database

Research Area

DATA IMAGES
GTX54377_20180530_WB_18121411_343.jpg

GTX54377 WB Image

WB analysis of various samples using GTX54377 MSH2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX54377_20180530_IP_18121411_928.jpg

GTX54377 IP Image

IP analysis of A549 cell lysate using GTX54377 MSH2 antibody.
IP reaction : 3μg antibody / 150μg cell lysate
Dilution : 1:1000