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MSH6 antibody [3E1-B11-F12]

Anti-MSH6 antibody [3E1-B11-F12] used in Western Blot (WB). GTX49251
Anti-MSH6 antibody [3E1-B11-F12] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49251

Cat. No. GTX49251

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3E1-B11-F12

Isotype

 IgG2a

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μg ($399)
See all MSH6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

153 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.5% BSA, 50% glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant fragment of human MSH6 expressed in E. Coli.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mutS homolog 6 , GTBP , GTMBP , HNPCC5 , HSAP , p160

Cellular Localization

Nucleus

Background

This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]

Database

Research Area

DATA IMAGES

Anti-MSH6 antibody [3E1-B11-F12] used in Western Blot (WB). GTX49251

GTX49251 WB Image

WB analysis of HCT116 and 293 lysates using MSH6 antibody.

Anti-MSH6 antibody [3E1-B11-F12] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49251

GTX49251 ICC/IF Image

ICC/IF analysis of HeLa cells using MSH6 antibody at a dilution of 1:100.

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399