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MSH6 antibody [44]

Anti-MSH6 antibody [44] used in IHC (Paraffin sections) (IHC-P). GTX73803

Cat. No. GTX73803

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 44

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
1 ml ($679)
See all MSH6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:25‐1:50

Note :

IHC-P
Recommendations for antigen retrieval : EDTA buffer pH 8.0 at room temperature for 30 mins.
Not tested in other applications.

Calculated MW

153 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human MSH6.

Purification

Purified IgG

Conjugation

Unconjugated

RRID

AB_383683

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

mutS homolog 6 , GTBP , GTMBP , HNPCC5 , HSAP , p160

Cellular Localization

Nucleus

Background

This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]

Database

Research Area

DATA IMAGES

Anti-MSH6 antibody [44] used in IHC (Paraffin sections) (IHC-P). GTX73803

GTX73803 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX73803 MSH6 antibody [44].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 679