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MSH6 antibody [PU29]

Cat No. GTX01885

Host

Mouse

Clonality

Monoclonal

Clone Name

PU29

Isotype

IgG1

Application

IHC-P

Reactivity

Human
Package
500 μl ($509)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:100

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections.

Not tested in other applications.

Calculated MW

153 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant, 15 mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

>200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to a 359 amino acid portion of the MSH6 human molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

mutS homolog 6 , GTBP , GTMBP , HNPCC5 , HSAP , p160

Cellular Localization

Nucleus

Background

This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]

Database

Research Area

REFERENCE

There are currently no references for MSH6 antibody [PU29] (GTX01885). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for MSH6 antibody [PU29] (GTX01885). Be the first to share your experience with this product.
Package List Price ($)
$ 509