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MT2A antibody

Anti-MT2A antibody used in IHC (Paraffin sections) (IHC-P). GTX00789
Anti-MT2A antibody used in Western Blot (WB). GTX00789
Anti-MT2A antibody used in IHC (Paraffin sections) (IHC-P). GTX00789

Cat. No. GTX00789

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Rat
Package
100 μl ($399)
See all MT2A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

6 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-61 of human MT2A (NP_005944.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Background

This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions, altering the intracellular concentration of heavy metals in the cell. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. The encoded protein interacts with the protein encoded by the homeobox containing 1 gene in some cell types, controlling intracellular zinc levels, affecting apoptotic and autophagy pathways. Some polymorphisms in this gene are associated with an increased risk of cancer. [provided by RefSeq, Sep 2017]

Database

Research Area

DATA IMAGES

Anti-MT2A antibody used in IHC (Paraffin sections) (IHC-P). GTX00789

GTX00789 IHC-P Image

IHC-P analysis of rat heart tissue using GTX00789 MT2A antibody.
Dilution : 1:200

Anti-MT2A antibody used in Western Blot (WB). GTX00789

GTX00789 WB Image

WB analysis of various sample lysates using GTX00789 MT2A antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-MT2A antibody used in IHC (Paraffin sections) (IHC-P). GTX00789

GTX00789 IHC-P Image

IHC-P analysis of human colon cancer tissue using GTX00789 MT2A antibody.
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399