APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 0.2-2.5 ug/ml |
| 2-10 ug/ml |
Not tested in other applications.
Calculated MW
Positive Control
HeLa , HepG2 , human fetal heart , human fetal lung , human ovary tumor , human placenta , MCF-7
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to an Internal region of Human MTUS1
Purification
Affinity Purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
microtubule associated scaffold protein 1 , ATBP , ATIP , ATIP3 , ICIS , MP44 , MTSG1
Cellular Localization
Mitochondrion,Golgi apparatus,Cell membrane,Nucleus
Background
This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX46731 WB Image
WB analysis of human MCF-7, HeLa, and human cancer cell lines using GTX46731 MTUS1 antibody at 1:2000.
Lane :
1 : MCF-7 cells
2 : MCF-7 cells over-expressing GFP tagged MTUS1 protein
3 : HeLa cells
4 and 5 : Human cancer cell lines
The observed size of endogenous MTUS1 protein is at ~180kDa, and GFP tagged MTSU1 protein is at ~210kDa.
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GTX46731 WB Image
WB analysis of human placenta tissue using GTX46731 MTUS1 antibody at 1μg/ml.
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GTX46731 WB Image
WB analysis of HepG2 cells using GTX46731 MTUS1 antibody at 1μg/ml.
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GTX46731 WB Image
WB analysis of human fetal heart tissue using GTX46731 MTUS1 antibody at 1μg/ml.
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GTX46731 WB Image
WB analysis of human fetal lung tissue using GTX46731 MTUS1 antibody at 1μg/ml.
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GTX46731 WB Image
WB analysis of HeLa cells using GTX46731 MTUS1 antibody at 0.2-1μg/ml.
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GTX46731 IHC-P Image
IHC-P analysis of human pineal tissue using GTX46731 MTUS1 antibody at 1:100. Left to right:DAPI, MTUS1, Merge. The low pH, heat-induced antigen retrieval method utilizing Sodium Citrate buffer was performed.
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GTX46731 WB Image
WB analysis of human placenta tissue using GTX46731 MTUS1 antibody at 1μg/ml.
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GTX46731 WB Image
WB analysis of human ovary tumor tissue using GTX46731 MTUS1 antibody at 1μg/ml.
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REFERENCE
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REVIEW
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