GeneTex

  • Country / Location Selection

United States (US)

MUC1 antibody [MUC1/2818R]

Anti-MUC1 antibody [MUC1/2818R] used in IHC (Paraffin sections) (IHC-P). GTX02678
Anti-MUC1 antibody [MUC1/2818R] used in IHC (Paraffin sections) (IHC-P). GTX02678

Cat. No. GTX02678

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 MUC1/2818R

Isotype

 IgG

Application

 IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($529)
See all MUC1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 0.25-0.5 μg/ml
ELISA 2-5 μg/ml (for coating)

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.

ELISA
For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human milk-fat globule membranes (HMFGM)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mucin 1, cell surface associated , ADMCKD , ADMCKD1 , CA 15-3 , CD227 , EMA , H23AG , KL-6 , MAM6 , MCD , MCKD , MCKD1 , MUC-1 , MUC-1/SEC , MUC-1/X , MUC1/ZD , PEM , PEMT , PUM

Cellular Localization

Apical cell membrane , Cytoplasm , Nucleus

Background

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES

Anti-MUC1 antibody [MUC1/2818R] used in IHC (Paraffin sections) (IHC-P). GTX02678

GTX02678 IHC-P Image

IHC-P analysis of human colon tissue section using GTX02678 MUC1 antibody [MUC1/2818R].

Anti-MUC1 antibody [MUC1/2818R] used in IHC (Paraffin sections) (IHC-P). GTX02678

GTX02678 IHC-P Image

IHC-P analysis of human stomach carcinoma section using GTX02678 MUC1 antibody [MUC1/2818R].

REFERENCE

There are currently no references for MUC1 antibody [MUC1/2818R] (GTX02678). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for MUC1 antibody [MUC1/2818R] (GTX02678). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 529