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MURF1 antibody

Anti-MURF1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33334
Anti-MURF1 antibody used in Western Blot (WB). GTX33334

Cat No. GTX33334

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($329)
See all MURF1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A synthetic peptide of human TRIM63

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

tripartite motif containing 63 , IRF , MURF1 , MURF2 , RNF28 , SMRZ

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012]

Database

DATA IMAGES

Anti-MURF1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33334

GTX33334 ICC/IF Image

ICC/IF analysis of A549 cell using GTX33334 MURF1 antibody.
Blue : DAPI

Anti-MURF1 antibody used in Western Blot (WB). GTX33334

GTX33334 WB Image

WB analysis of mouse heart tissue lysate using GTX33334 MURF1 antibody.
Dilution : 1:400
Loading : 25μg per lane

REFERENCE

Application Reference

Lee SJ et al. J Ethnopharmacol 2019; 242 : 112054 Ginsenoside Rg3 upregulates myotube formation and mitochondrial function, thereby protecting myotube atrophy induced by tumor necrosis factor-alpha.
Application : WB
Reactivity : Mouse
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REVIEW

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Package List Price ($)
$ 329