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MVP/LRP antibody [0.N.389] (Azide free)

Anti-MVP/LRP antibody [0.N.389] (Azide free) used in IHC (Paraffin sections) (IHC-P). GTX14563

Cat. No. GTX14563

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 0.N.389

Isotype

 IgG1

Application

 WB, IHC-P, FACS, IP

Reactivity

 Human, Rat
Package
50 μg ($489)
See all MVP/LRP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P 1:50-1:100
FACS Assay dependent
IP 2μg antibody/mg native protein lysate (Use Protein G)

Note :

IHC-P
Antigen retireval : Requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10-20 minutes, followed by cooling at RT for 20 minutes
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Proteins purified from extract of human breast cancer MCF-7 cells.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

LRP , MVP , VAULT1 , major vault protein

Cellular Localization

Cytoplasm,Nucleus,Nuclear pore complex

Background

This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]

Database

Research Area

DATA IMAGES

Anti-MVP/LRP antibody [0.N.389] (Azide free) used in IHC (Paraffin sections) (IHC-P). GTX14563

GTX14563 IHC-P Image

IHC-P analysis of human breast cancer tissue using GTX14563 MVP/LRP antibody [0.N.389] (Azide free).

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 489