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MVP/LRP antibody [C2C3], C-term

KO/KD
Anti-MVP/LRP antibody [C2C3], C-term used in Western Blot (WB). GTX100536
Anti-MVP/LRP antibody [C2C3], C-term used in Western Blot (WB). GTX100536
Anti-MVP/LRP antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100536

Cat No. GTX100536

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($329),
25 μl ($169)
See all MVP/LRP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

Positive Control

HeLa , NIH-3T3

Predict Reactivity

Rat, Bovine, Cat, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

1XPBS (pH7), 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human MVP/LRP. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1241030

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

major vault protein , LRP , VAULT1

Cellular Localization

Cytoplasm , Nucleus , nuclear pore complex

Background

This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-MVP/LRP antibody [C2C3], C-term used in Western Blot (WB). GTX100536

GTX100536 WB Image

KO/KD

Wild-type (WT) and MVP/LRP knockout (KO) HeLa cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with MVP/LRP antibody [C2C3], C-term (GTX100536) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-MVP/LRP antibody [C2C3], C-term used in Western Blot (WB). GTX100536

GTX100536 WB Image

Sample (30 μg of whole cell lysate)
A:NIH-3T3
7.5% SDS PAGE
GTX100536 diluted at 1:1000
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-MVP/LRP antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100536

GTX100536 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human gastric , using MVP/LRP(GTX100536) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

REFERENCE

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REVIEW

There are currently no reviews for MVP/LRP antibody [C2C3], C-term (GTX100536). Be the first to share your experience with this product.
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SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 329
$ 169