GeneTex

  • Country / Location Selection

United States (US)

MVP/LRP antibody [LMR5]

Cat. No. GTX23374

Host

 Rat

Clonality

 Monoclonal

Clone Name

 LMR5

Isotype

 IgG

Application

 IHC-P, IHC-Fr, FACS

Reactivity

 Human
Package
500 μl ($399)
See all MVP/LRP products

APPLICATION

Application Note

FACS: use at a diluton of 1/20 - 1/30. Cell permeabilization required. IHC-P: use at a diluton of 1/20 - 1/30. IHC-Fr: use at a diluton of 1/20 - 1/30. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

99 kDa. ( Note )

Positive Control

Positive tissue - Cell Lines: Drug-sensitive parental cell lines and their multidrugresistant derivativesNegative control antibody: Normal rat serum

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Tissue / cell preparation; 2R120 cell line, derived by stepwise Doxorubicin exposure of the SW-1573 non-small cell lung carcinoma cell line.

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

major vault protein , LRP , VAULT1

Cellular Localization

Cytoplasm

Background

This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]

Database

Research Area

REFERENCE

There are currently no references for MVP/LRP antibody [LMR5] (GTX23374). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for MVP/LRP antibody [LMR5] (GTX23374). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399