MX1 antibody [HL2051]

Name: MX1 antibody [HL2051]
Brand: GeneTex
SKU: GTX637955
Price: 399.00 USD
Rating: 5 (1 reviews)

Anti-MX1 antibody [HL2051] used in Western Blot (WB). GTX637955

Anti-MX1 antibody [HL2051] used in IHC (Paraffin sections) (IHC-P). GTX637955

Cat. No. GTX637955

Host	Rabbit
Clonality	Monoclonal
Clone Name	HL2051
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human, Mouse, Cat, Dog
Package	100 μl ($399), 25 μl ($169)

See all MX1 products

Datasheet

View product citations for antibody GTX637955 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500-1:3000
IHC-P	Assay dependent

Not tested in other applications.

Calculated MW

76 kDa. ( Note )

Product Note

This antibody is specific for human MX1 protein, and it does not cross react with human MX2 protein.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of human MX1

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

MX dynamin like GTPase 1 , IFI-78K , IFI78 , MX , MxA

Cellular Localization

Cytoplasm,Endoplasmic reticulum membrane,Cytoplasm, perinuclear region,Nucleus

Background

This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Database

Gene ID: 4599 MX1
UniProt: P20591 MX1

Research Area

DATA IMAGES

GTX637955 WB Image

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with MX1 antibody [HL2051] (GTX637955) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX637955 IHC-P Image

MX1 antibody [HL2051] detects MX1 protein at cytoplasm and nucleus by immunohistochemical analysis.
Sample: Paraffin-embedded human lung cancer.
MX1 stained by MX1 antibody [HL2051] (GTX637955) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX637955 IHC-P Image

MX1 antibody [HL2051] detects MX1 protein at cytoplasm and nucleus by immunohistochemical analysis.
Sample: Paraffin-embedded mouse kidney.
MX1 stained by MX1 antibody [HL2051] (GTX637955) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX637955 WB Image

Whole cell extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with MX1 antibody [HL2051] (GTX637955) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX637955 WB Image

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with MX1 antibody [HL2051] (GTX637955) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.

GTX637955 IHC-P Image

MX1 antibody [HL2051] detects MX1 protein at cytoplasm and nucleus by immunohistochemical analysis.
Sample: Paraffin-embedded cat kidney.
MX1 stained by MX1 antibody [HL2051] (GTX637955) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

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REVIEW