GeneTex
United States (US)

MYSM1 antibody

MYSM1-antibody-GTX87695-IHC-1_18121411_675.jpg

Cat No. GTX87695

Host Rabbit
Clonality Polyclonal
Application IHC-P, ELISA
Reactivity Human
APPLICATION

Application Note

We recommend the following starting dilutions:

IHC: 1:50~1:100
ELISA: 1:40000

Optimal dilutions should be determined experimentally by the end user.

Calculated MW

95 kDa. ( Note )

Specificity/Sensitivity

MYSM1 Antibody detects endogenous levels of total MYSM1 protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 229% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human MYSM1.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Myb Like, Swirm And Mpn Domains 1,2A-Dub,2Adub,Mysm1

Background

Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.

Database

DATA IMAGES
MYSM1-antibody-GTX87695-IHC-1_18121411_675.jpg

GTX87695 IHC-P Image

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using MYSM1 Antibody. The picture on the right is treated with the synthesized peptide.

Package List Price ($)
$ 339