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MYST2 antibody [N2C1], Internal

KO/KD
Anti-MYST2 antibody [N2C1], Internal used in Western Blot (WB). GTX102041
Anti-MYST2 antibody [N2C1], Internal used in IHC (Paraffin sections) (IHC-P). GTX102041
Anti-MYST2 antibody [N2C1], Internal used in Western Blot (WB). GTX102041
Anti-MYST2 antibody [N2C1], Internal used in Western Blot (WB). GTX102041
Anti-MYST2 antibody [N2C1], Internal used in Western Blot (WB). GTX102041
Anti-MYST2 antibody [N2C1], Internal used in Western Blot (WB). GTX102041

Cat. No. GTX102041

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all MYST2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

Positive Control

MCF-7 , Mouse brain

Predict Reactivity

Rat, Bovine, Chicken, Pig, Xenopus tropicalis(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.33 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human MYST2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_10720166

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

lysine acetyltransferase 7 , HBO1 , HBOA , MYST2 , ZC2HC7

Cellular Localization

Nucleus , nucleoplasm

Background

Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.

Database

Research Area

DATA IMAGES

Anti-MYST2 antibody [N2C1], Internal used in Western Blot (WB). GTX102041

GTX102041 WB Image

Sample (30 ug of whole cell lysate)
A: MCF-7
7.5% SDS PAGE
GTX102041 diluted at 1:1000

Anti-MYST2 antibody [N2C1], Internal used in IHC (Paraffin sections) (IHC-P). GTX102041

GTX102041 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human hepatoma, using MYST2(GTX102041) antibody at 1:250 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-MYST2 antibody [N2C1], Internal used in Western Blot (WB). GTX102041

GTX102041 WB Image

Sample (50 ug of whole cell lysate)
A: Mouse brain
7.5% SDS PAGE
GTX102041 diluted at 1:1000

Anti-MYST2 antibody [N2C1], Internal used in Western Blot (WB). GTX102041

GTX102041 WB Image

KO/KD

The data was published in the journal Oncotarget in 2016. PMID: 26625199

Anti-MYST2 antibody [N2C1], Internal used in Western Blot (WB). GTX102041

GTX102041 WB Image

The data was published in the journal Oncotarget in 2016. PMID: 26625199

Anti-MYST2 antibody [N2C1], Internal used in Western Blot (WB). GTX102041

GTX102041 WB Image

The data was published in the journal Oncotarget in 2016. PMID: 26625199

REFERENCE

Application Reference

Zhang X et al. J Virol 2024; 98 (3) : e0169523 NS1-mediated enhancement of MVC transcription and replication promoted by KAT5/H4K12ac.
Wright DG et al. Oncotarget 2016; 7 (2) : 1687-706 Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169