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Mannose Receptor antibody [7-450]

Anti-Mannose Receptor antibody [7-450] used in IHC (Frozen sections) (IHC-Fr). GTX42267

Cat. No. GTX42267

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 7-450

Isotype

 IgG2a

Application

 IHC-Fr

Reactivity

 Human
Package
200 μg ($459)
See all Mannose Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr 1/50-1/500
Not tested in other applications.

Calculated MW

166 kDa. ( Note )

Product Note

This antibody recognizes human CD206, otherwise known as macrophage mannose receptor (MMR).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Monocyte-derived dendritic cells.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mannose receptor C-type 1 , CD206 , CLEC13D , CLEC13DL , MMR , MRC1L1 , bA541I19.1 , hMR

Cellular Localization

Endosome membrane , Cell membrane

Background

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-Mannose Receptor antibody [7-450] used in IHC (Frozen sections) (IHC-Fr). GTX42267

GTX42267 IHC-Fr Image

IHC-Fr analysis of human tonsil tissue using GTX42267 Mannose Receptor antibody [7-450].

REFERENCE

Clone Reference

Blagojevi? V et al. Life Sci 2018; (Epub) Rat strain differences in peritoneal immune cell response to selected gut microbiota: A crossroad between tolerance and autoimmunity-
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 459