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Mannose Receptor antibody

Anti-Mannose Receptor antibody used in Flow cytometry (FACS). GTX03378
Anti-Mannose Receptor antibody used in Flow cytometry (FACS). GTX03378

Cat. No. GTX03378

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS

Reactivity

 Human, Mouse, Rat, Dog
Package
100 μl ($399)
See all Mannose Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:300-5000
IHC-P 1:200-400
FACS 1:20-100
Not tested in other applications.

Calculated MW

166 kDa. ( Note )

Predict Reactivity

Sheep, Bovine, Chicken, Guinea pig, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

1% BSA, 50% glycerol

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human MRC1 (201-300).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mannose receptor C-type 1 , CD206 , CLEC13D , CLEC13DL , MMR , MRC1L1 , bA541I19.1 , hMR

Cellular Localization

Endosome membrane , Cell membrane

Background

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-Mannose Receptor antibody used in Flow cytometry (FACS). GTX03378

GTX03378 FACS Image

FACS analysis of HepG2 cells using GTX03378 Mannose Receptor antibody. Acquisitions of 20,000 events were performed.
Green : Primary antibody
Orange : Isotype control
Dilution : 1:50

Anti-Mannose Receptor antibody used in Flow cytometry (FACS). GTX03378

GTX03378 FACS Image

FACS analysis of 4% PFA-fixed THP-1 cells using GTX03378 Mannose Receptor antibody. Acquisitions of 20,000 events were performed.
Green : Primary antibody
Orange : Isotype control
Permeabilization : 0.1%PBST for 20 min at room temperature
Dilution : 1:50

REFERENCE

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REVIEW

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Package List Price ($)
$ 399