GeneTex

  • Country / Location Selection

United States (US)

Melanoma antibody [HMB45] (ready-to-use)

Anti-Melanoma antibody [HMB45] (ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX20906

Cat. No. GTX20906

Reference 3

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 HMB45

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
6 ml ($399)
See all Melanoma products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P Assay dependent

Note :

IHC-P
Recommendations for antigen retrieval : Citrate Buffer pH 6.0 at room temperature for 30 mins.
Not tested in other applications.

Product Note

This antibody reacts with a neuraminidase sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes. It reacts with junctional and blue nevus cells. Non-melanocytic cells are negative.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

BALB/C mice were injected with extract of pigmented melanoma metastases from lymph nodes.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Research Area

DATA IMAGES

Anti-Melanoma antibody [HMB45] (ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX20906

GTX20906 IHC-P Image

IHC-P analysis of human melanoma tissue using GTX20906 Melanoma antibody [HMB45] (ready-to-use).

REFERENCE

Clone Reference

Yang CF et al. Am J Hum Genet 2018; 102 (2):219-232 Loss of GPNMB Causes Autosomal-Recessive Amyloidosis Cutis Dyschromica in Humans.
Lee E et al. Br J Dermatol 2016; ITAC induces the melanocytic migration and hypopigmentation through destabilizing p53 via HDAC5: A possible role of ITAC in pigment-related disorders.
Bin BH et al. PLoS One 2014; 9 (8):e105965 Hyperosmotic stress reduces melanin production by altering melanosome formation.
Submit a Reference

REVIEW

There are currently no reviews for Melanoma antibody [HMB45] (ready-to-use) (GTX20906). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399