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Melanopsin antibody

Anti-Melanopsin antibody used in Immunohistochemistry (IHC). GTX19383

Cat. No. GTX19383

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-Fr, IHC

Reactivity

 Human, Mouse, Rat, Rodent
Package
100 μg ($399)
See all Melanopsin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1 - 0.2 μg/ml
ICC/IF 5 μg/ml
IHC-Fr 1:1000
IHC Assay dependent
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

Product Note

This antibody can detect over-expressed melanopsin protein but it does not work well on endogenously expressed protein.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Synthetic peptide corresponding to residues E(455) Q K S K T P K T K R H L P S L D R R M(474) of rat melanopsin.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_423559

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

opsin 4

Cellular Localization

Cell membrane

Background

visual pigment of phototransducing retinal ganglion cells involved in setting the circadian clock [RGD, Feb 2006]

Database

Research Area

DATA IMAGES

Anti-Melanopsin antibody used in Immunohistochemistry (IHC). GTX19383

GTX19383 IHC Image

IHC analysis of rat retinal ganglion cells using GTX19383 Melanopsin antibody.

REFERENCE

Application Reference

Fan J et al. Exp Eye Res 2021; 209 : 108698 Retbindin mediates light-damage in mouse retina while its absence leads to premature retinal aging.
Application : WB
Reactivity : Mouse
Vogt D et al. Curr Eye Res 2020; : 1-8 Premacular Cells as Source of Neurotrophic Factors in Idiopathic Macular Holes.
Schumann RG et al. Ophthalmologica 2019; : 1-7 Premacular Cell Proliferation Profiles in Tangential Traction Vitreo-Maculopathies Suggest a Key Role for Hyalocytes.
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399