GeneTex

  • Country / Location Selection

United States (US)

Melatonin Receptor 1A antibody, Internal

Anti-Melatonin Receptor 1A antibody, Internal used in Western Blot (WB). GTX31054

Cat. No. GTX31054

Reference 2

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Rat, Deer
Package
100 μg ($399)
See all Melatonin Receptor 1A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-3μg/ml
Not tested in other applications.

Calculated MW

39 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX31054-PEP).

Predict Reactivity

Human, Mouse, Bovine, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-SLKYDKLYSSKNS, from the internal region of the protein sequence according to NP_005949.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

melatonin receptor 1A , MEL-1A-R , MT1

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Melatonin Receptor 1A antibody, Internal used in Western Blot (WB). GTX31054

GTX31054 WB Image

WB analysis of rat retina lysate using GTX31054 Melatonin Receptor 1A antibody, Internal.
Dilution : 0.1μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

Application Reference

Xuyang Sun et al. Int J Mol Sci 2022; 23 (2) Melatonin Promotes Antler Growth by Accelerating MT1-Mediated Mesenchymal Cell Differentiation and Inhibiting VEGF-Induced Degeneration of Chondrocytes.
Application : WB
Reactivity : Deer
Sun X et al. Int. J. Mol. Sci. 2022; 23 (2) : 759 Melatonin Promotes Antler Growth by Accelerating MT1-Mediated Mesenchymal Cell Differentiation and Inhibiting VEGF-Induced Degeneration of Chondrocytes.
Application : WB
Submit a Reference

REVIEW

There are currently no reviews for Melatonin Receptor 1A antibody, Internal (GTX31054). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399