APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| 1:500-1:1000 |
| 1:50-1:100 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide sequence around aa.516~520 (R-L-S-M-E) derived from human Merlin.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
neurofibromin 2 , ACN , BANF , SCH
Cellular Localization
Nucleus,Cytoplasm, cytoskeleton
Background
This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX50579 WB Image
WB analysis of extracts from mouse brain tissue and C6 cells using GTX50579 Merlin antibody.
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GTX50579 IHC-P Image
IHC-P analysis of human lung carcinoma tissue using GTX50579 Merlin antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide
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REFERENCE
There are currently no references for Merlin antibody (GTX50579). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Merlin antibody (GTX50579). Be the first to share your experience with this product.
