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Mesothelin antibody [TCL1/2747R]

Anti-Mesothelin antibody [TCL1/2747R] used in IHC (Paraffin sections) (IHC-P). GTX02676
Anti-Mesothelin antibody [TCL1/2747R] used in IHC (Paraffin sections) (IHC-P). GTX02676

Cat. No. GTX02676

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 TCL1/2747R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all Mesothelin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2 μg/ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

69 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human TCL1 protein fragment (around aa 2-109)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mesothelin , MPF , SMRP

Cellular Localization

Golgi apparatus

Background

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Database

Research Area

DATA IMAGES

Anti-Mesothelin antibody [TCL1/2747R] used in IHC (Paraffin sections) (IHC-P). GTX02676

GTX02676 IHC-P Image

IHC-P analysis of human tonsil tissue section using GTX02676 Mesothelin antibody [TCL1/2747R].

Anti-Mesothelin antibody [TCL1/2747R] used in IHC (Paraffin sections) (IHC-P). GTX02676

GTX02676 IHC-P Image

IHC-P analysis of human tonsil tissue section using GTX02676 Mesothelin antibody [TCL1/2747R].

REFERENCE

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REVIEW

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Package List Price ($)
$ 529