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Mesothelin antibody [YP158]

Anti-Mesothelin antibody [YP158] used in IHC (Paraffin sections) (IHC-P). GTX03327

Cat. No. GTX03327

Host

Rabbit

Clonality

Monoclonal

Clone Name

YP158

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
500 μl ($449)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:10-1:15

Note :

IHC-P
Pretreatment : EDTA Buffer pH 8.0 for 30 min at RT

Not tested in other applications.

Calculated MW

69 kDa. ( Note )

Positive Control

Mesothelioma

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to c-terminus of human mesothelin protein

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mesothelin , MPF , SMRP

Cellular Localization

Golgi apparatus

Background

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Database

Research Area

DATA IMAGES

Anti-Mesothelin antibody [YP158] used in IHC (Paraffin sections) (IHC-P). GTX03327

GTX03327 IHC-P Image

IHC-P analysis of human mesothelioma tissue section using GTX03327 Mesothelin antibody [YP158].

REFERENCE

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REVIEW

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Package List Price ($)
$ 449