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MettL7B antibody

Anti-MettL7B antibody used in Western Blot (WB). GTX85368
Anti-MettL7B antibody used in IHC (Paraffin sections) (IHC-P). GTX85368

Cat. No. GTX85368

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($419)
See all METTL7B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

Positive Control

Human Colon Tissue Lysate(GTX27928) , Human Spleen Tissue Slide

Product Note

This MettL7B antibody is predicted to not cross-react with MettL7A.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

MettL7B antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human MettL7B.The immunogen is located within amino acids 20 - 70 of MettL7B.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

methyltransferase like 7B , ALDI

Background

MettL7b belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. This MettL7B antibody is predicted to not cross-react with MettL7A.

Database

DATA IMAGES

Anti-MettL7B antibody used in Western Blot (WB). GTX85368

GTX85368 WB Image

WB analysis of human colon tissue lysate using GTX85368 MettL7B antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-MettL7B antibody used in IHC (Paraffin sections) (IHC-P). GTX85368

GTX85368 IHC-P Image

IHC-P analysis of human spleen tissue using GTX85368 MettL7B antibody.
Working concentration : 2.5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419