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Mineralocorticoid Receptor antibody, Internal

Anti-Mineralocorticoid Receptor antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX46537
Anti-Mineralocorticoid Receptor antibody, Internal used in Western Blot (WB). GTX46537

Cat. No. GTX46537

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all Mineralocorticoid Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

107 kDa. ( Note )

Positive Control

A172

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to an Internal region of Human Mineralocorticoid Receptor

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

nuclear receptor subfamily 3 group C member 2 , MCR , MLR , MR , NR3C2VIT

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Database

Research Area

DATA IMAGES

Anti-Mineralocorticoid Receptor antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX46537

GTX46537 IHC-P Image

IHC-P analysis of human kidney tissue using GTX46537 Mineralocorticoid Receptor antibody at 4.0-8.0μg/ml.

Anti-Mineralocorticoid Receptor antibody, Internal used in Western Blot (WB). GTX46537

GTX46537 WB Image

WB analysis of A172 cells using GTX46537 Mineralocorticoid Receptor antibody at 1.25μg/ml.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399