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Mineralocorticoid Receptor antibody

Anti-Mineralocorticoid Receptor antibody used in Western Blot (WB). GTX00779
Anti-Mineralocorticoid Receptor antibody used in Western Blot (WB). GTX00779

Cat. No. GTX00779

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
100 μg ($429)
See all Mineralocorticoid Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.5μg/ml
Not tested in other applications.

Calculated MW

107 kDa. ( Note )

Product Note

Superfamily members of NR3C2 are not reactive to this antibody.

Predict Reactivity

Chicken(>80% identity)

PROPERTIES

Form

Liquid

Buffer

5mg BSA, 0.9mg NaCl, 0.2mg Na₂HPO₄

Preservative

0.05mg Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

This antibody was raised against a synthetic peptide corresponding to a sequence at the C-terminus of human NR3C2 (950-984aa HALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

nuclear receptor subfamily 3 group C member 2 , MCR , MLR , MR , NR3C2VIT

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Database

Research Area

DATA IMAGES

Anti-Mineralocorticoid Receptor antibody used in Western Blot (WB). GTX00779

GTX00779 WB Image

WB analysis of various samples using GTX00779 Mineralocorticoid Receptor antibody.
Lane 1 : Mouse Brain Tissue Lysate
Lane 2 : Rat Brain Tissue Lysate
Dilution : 0.5 μg/mL
Loading : 50μg

Anti-Mineralocorticoid Receptor antibody used in Western Blot (WB). GTX00779

GTX00779 WB Image

WB analysis of various samples using GTX00779 Mineralocorticoid Receptor antibody.
Lane 1 : Rat Kidney Tissue Lysate
Lane 2 : Mouse Kidney Tissue Lysate
Lane 3 : HeLa Whole Cell Lysate
Lane 4 : A431 Whole Cell Lysate
Dilution : 0.5 μg/mL
Loading : 50μg

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 429