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Mineralocorticoid Receptor antibody

Anti-Mineralocorticoid Receptor antibody used in Western Blot (WB). GTX37373

Cat. No. GTX37373

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Rat
Package
100 μg ($399)
See all Mineralocorticoid Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
Not tested in other applications.

Calculated MW

107 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.01M TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 611-690 amino acids of human MR

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

nuclear receptor subfamily 3 group C member 2 , MCR , MLR , MR , NR3C2VIT

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Database

Research Area

DATA IMAGES

Anti-Mineralocorticoid Receptor antibody used in Western Blot (WB). GTX37373

GTX37373 WB Image

WB analysis of rat brain (Lane 1), rat kidney (Lane 2) tissue lysates using GTX37373 Mineralocorticoid Receptor antibody.
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399