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Mouse ACVRL1 protein, human IgG1 Fc and His tag (active)

Mouse ACVRL1 protein, human IgG1 Fc and His tag (active). GTX01430-pro
Mouse ACVRL1 protein, human IgG1 Fc and His tag (active). GTX01430-pro

Cat No. GTX01430-pro

Application

Functional Assay

Species

Mouse
Package
200 μg ($329),
100 μg ($249)

APPLICATION

Application Note

Measured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3-E1 cells. The ED₅₀ for this effect is typically 60-300 ng/ml in the presence of 2 ng/ml of recombiant human BMP9 protein.

Calculated MW

57 kDa. ( Note )

Observed MW

50-55 kDa.

PROPERTIES

Form

Lyophilized powder

Buffer

Batch dependent (please contact us for details)

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.

Region/Sequence

C-terminal human IgG1-Fc and poly His tagged; Met1-Pro119 of Mouse ACVRL1 protein (NP_033742.2)

Expression System

HEK293 cells

Purity

> 95% by SDS-PAGE.

Endotoxin

< 1.0 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

activin A receptor, type II-like 1 , AI115505 , AI427544 , Acvrlk1 , Alk1

Cellular Localization

Cell membrane

Database

Research Area

DATA IMAGES

Mouse ACVRL1 protein, human IgG1 Fc and His tag (active). GTX01430-pro

GTX01430-pro Functional Assay Image

The protein activity of GTX01430-pro Mouse ACVRL1 protein was measured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3-E1 cells.
ED₅₀ : 60-300 ng/ml in the presence of 2 ng/ml of recombiant human BMP9 protein

Mouse ACVRL1 protein, human IgG1 Fc and His tag (active). GTX01430-pro

GTX01430-pro Image

SDS-PAGE of 5 μg GTX01430-pro Mouse ACVRL1 protein, human IgG1 Fc and His tag (active).

REFERENCE

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REVIEW

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Package List Price ($)
$ 329
$ 249