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Mouse CTLA4 protein, mouse IgG2a Fc tag (active)

Cat. No. GTX65759-pro

Application

Functional Assay

Species

Mouse
Package
100 μg ($219)

APPLICATION

Application Note

Binds both CD80 (B7-1) and CD86 (B7-2) with high affinity and inhibits CD28 signaling competitively. Kills the target cell completely.

PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with ddH₂O to 1mg/ml. Lyophilized from 0.2μm-filtered PBS.

Preservative

No preservative

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and avoid freeze-thaw cycles.

Region/Sequence

The extracellular domain of mouse CD152 [CTLA-4] (a.a. 38-160) is fused to the N-terminus of the Fc region of mouse IgG2a.

Expression System

NS-1 cells

Purity

??98% by SDS-PAGE.

Endotoxin

< 0.06 EU/μg

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

cytotoxic T-lymphocyte-associated protein 4 , Cd152 , Ctla-4 , Ly-56

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 219