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Mouse FGFR1 protein, human IgG1 Fc tag (active)

Mouse FGFR1 protein, human IgG1 Fc tag (active). GTX01384-pro
Mouse FGFR1 protein, human IgG1 Fc tag (active). GTX01384-pro

Cat No. GTX01384-pro

Application

Functional Assay

Species

Mouse
Package
100 μg ($359),
50 μg ($259)

APPLICATION

Application Note

Measured by its ability to inhibit mouse FGF-acidic (aFGF/FGF1) dependent proliferation of Balb/c 3T3 cells. The ED₅₀ for this effect is typically 6-25 ng/ml in the presence of 0.5 ng/ml of mouse FGF-acidic (aFGF/FGF1) protein.

Calculated MW

92 kDa. ( Note )

Observed MW

100-110 kDa.

PROPERTIES

Form

Lyophilized powder

Buffer

Batch dependent (please contact us for details)

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.

Region/Sequence

C-terminal human IgG1-Fc tagged; Met1-Glu376 of Mouse FGFR1 protein (P16092-1)

Expression System

HEK293 cells

Purity

> 97% by SDS-PAGE.

Endotoxin

< 1.0 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

fibroblast growth factor receptor 1 , AW208770 , Eask , FGFR-I , FLG , Fgfr-1 , Flt-2 , Hspy , MFR , bFGF-R-1 , c-fgr

Cellular Localization

Cell membrane; Single-pass type I membrane protein , Nucleus , Cytoplasm, cytosol , Cytoplasmic vesicle

Database

Research Area

DATA IMAGES

Mouse FGFR1 protein, human IgG1 Fc tag (active). GTX01384-pro

GTX01384-pro Image

SDS-PAGE of 5 μg GTX01384-pro Mouse FGFR1 protein, human IgG1 Fc tag (active).

Mouse FGFR1 protein, human IgG1 Fc tag (active). GTX01384-pro

GTX01384-pro Functional Assay Image

The protein activity of GTX01384-pro Mouse FGFR1 protein was measured by its ability to inhibit FGF-acidic (aFGF / FGF1) induced Balb/c 3T3 cells proliferation.
ED₅₀ : 6-25 ng/ml in the presence of 0.5 ng/ml of mouse FGF acidic (aFGF/FGF1) protein

REFERENCE

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REVIEW

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Package List Price ($)
$ 359
$ 259