Mouse FGFR1 protein, human IgG1 Fc tag (active)

Cat No. GTX01384-pro

Application	Functional Assay
Species	Mouse
Package	100 μg ($359), 50 μg ($259)

See all FGFR1 protein products

Datasheet

APPLICATION

Application Note

Measured by its ability to inhibit mouse FGF-acidic (aFGF/FGF1) dependent proliferation of Balb/c 3T3 cells. The ED₅₀ for this effect is typically 6-25 ng/ml in the presence of 0.5 ng/ml of mouse FGF-acidic (aFGF/FGF1) protein.

Calculated MW

92 kDa. ( Note )

Observed MW

100-110 kDa.

PROPERTIES

Form

Lyophilized powder

Buffer

Batch dependent (please contact us for details)

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.

Region/Sequence

C-terminal human IgG1-Fc tagged; Met1-Glu376 of Mouse FGFR1 protein (P16092-1)

Expression System

HEK293 cells

Purity

> 97% by SDS-PAGE.

Endotoxin

< 1.0 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

fibroblast growth factor receptor 1 , AW208770 , Eask , FGFR-I , FLG , Fgfr-1 , Flt-2 , Hspy , MFR , bFGF-R-1 , c-fgr

Cellular Localization

Cell membrane; Single-pass type I membrane protein , Nucleus , Cytoplasm, cytosol , Cytoplasmic vesicle

Database

Gene ID: 14182 Fgfr1
UniProt: P16092 Fgfr1

Research Area

DATA IMAGES

GTX01384-pro Functional Assay Image

The protein activity of GTX01384-pro Mouse FGFR1 protein was measured by its ability to inhibit FGF-acidic (aFGF / FGF1) induced Balb/c 3T3 cells proliferation.
ED₅₀ : 6-25 ng/ml in the presence of 0.5 ng/ml of mouse FGF acidic (aFGF/FGF1) protein

GTX01384-pro Image

SDS-PAGE of 5 μg GTX01384-pro Mouse FGFR1 protein, human IgG1 Fc tag (active).

REFERENCE

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REVIEW

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Package

List Price ($)

100 μg

$ 359

50 μg

$ 259

Qty