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Mouse GITRL protein, DDDDK tag (active)

Mouse GITRL protein, DDDDK tag (active). GTX65629-pro

Cat. No. GTX65629-pro

Application

Functional Assay

Species

Mouse
Package
50 μg ($499)

APPLICATION

Application Note

Induces GITR-mediated NF-κB activation in HEK 293 cells.

Product Note

Binds to mouse GITR.

PROPERTIES

Form

Liquid

Buffer

10mM Glycine (pH10.0)

Preservative

No preservative

Storage

Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

N-terminal DDDDK-Tag; the extracellular domain of mouse GITRL (a.a. 45-173).

Expression System

HEK293 cells

Purity

??90% by SDS-PAGE.

Endotoxin

< 0.1 EU/μg

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

tumor necrosis factor (ligand) superfamily, member 18 , Gitrl , Tnlg2a

Database

Research Area

DATA IMAGES

Mouse GITRL protein, DDDDK tag (active). GTX65629-pro

GTX65629-pro Image

GTX65629-pro GITRL protein induced GITR-mediated NF-κB activation. HEK293 cells were transiently transfected with 20ng of a (NF-κB)-Luc reporter, 2ng of a Renilla luciferase, and with 20ng of a GITR full length encoding construct. At 24hr after transfection, the indicated amounts of GITRL protein or a DDDDK control protein were treated for 4hr and followed by the measurement of dual luciferase activities.

REFERENCE

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REVIEW

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Package List Price ($)
$ 499