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Mouse IL6 protein, His tag (active)

Mouse IL6 protein, His tag (active). GTX67072-pro

Cat No. GTX67072-pro

Application

Functional Assay

Species

Mouse
Package
50 μg ($289)

APPLICATION

Application Note

Measured in a cell proliferation assay using M-NFS-60 mouse B cells. The ED₅₀ for this effects is less or equal to 0.1 ng/ml.

Observed MW

18-28 kDa.

PROPERTIES

Form

Liquid

Buffer

PBS (pH 7.4) with 10% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml

Region/Sequence

C-terminal His-Tag; Length: 193 a.a. Sequence: FPTSQVRRGD FTEDTTPNRP VYTTSQVGGL ITHVLWEIVE MRKELCNGNS DCMNNDDALA ENNLKLPEIQ RNDGCYQTGY NQEICLLKIS SGLLEYHSYL EYMKNNLKDN KKDKARVLQR DTETLIHIFN QEVKDLHKIV LPTPISNALL TDKLESQKEW LRTKTIQFIL KSLEEFLKVT LRSTRQTHHH HHH

Expression System

Baculovirus

Purity

> 95% by SDS-PAGE.

Endotoxin

< 1.0 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

interleukin 6 , Il-6

Background

This gene encodes a member of the interleukin family of cytokines that have important functions in immune response, hematopoiesis, inflammation and the acute phase response. The ectopic overexpression of the encoded protein in mice results in excessive plasma cells in circulation, leading to death. Mice lacking the encoded protein exhibit abnormalities in hepatic acute phase response, some immune mechanisms, bone resorption in response to estrogen, liver regeneration and wound healing. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Mouse IL6 protein, His tag (active). GTX67072-pro

GTX67072-pro Image

3 μg of GTX67072-pro Mouse IL6 protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain

REFERENCE

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SDS
PBS.pdf
Glycerol.pdf
Package List Price ($)
$ 289