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Mouse IgG2c isotype control [6.3] (Biotin)

Cat. No. GTX35013

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 6.3

Isotype

 IgG2c

Application

 FACS, ELISA
Package
50 μg ($79)
See all Mouse IgG2c isotype control products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent
ELISA Assay dependent
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS, stabilizer

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Conjugation

Biotin

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Mouse isotype control for , Mouse negative control , Mouse isotype control , Mouse isotype control , Isotype control to Mouse , Isotype control for Mouse , Mouse negative control for , Negative control for Mouse

Background

Inclusion of an appropriate isotype control is essential for the proper interpretation of experimental results. Because isotype control antibodies have no relevant specificity, they enable the researcher to distinguish non-specific "background" binding from antigen-specific antibody binding. Non-specific binding of primary antibodies may occur due to either binding of antibody to Fc receptors or non-specific interactions with cellular proteins, lipids, or carbohydrates. Additionally, autofluorescence or endogenous enzyme activity in target cells may give a false positive that could be misinterpreted as antibody binding. These factors vary by target cell type and the isotype of the primary antibody. Therefore, the primary antibody used should be matched to an isotype control of identical species and isotype (including both heavy and light chains).

REFERENCE

Clone Reference

Lewis PE et al. Vaccines (Basel) 2020; 8 (2) CTLA-4 Blockade, during HIV Virus-Like Particles Immunization, Alters HIV-Specific B-Cell Responses.
Bootz A et al. PLoS Pathog 2017; 13 (8):e1006601 Protective capacity of neutralizing and non-neutralizing antibodies against glycoprotein B of cytomegalovirus.
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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 79