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Mouse IgG2c isotype control [6.3]

Cat. No. GTX35043

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 6.3

Isotype

 IgG2c

Application

 ELISA
Package
50 μg ($79)
See all Mouse IgG2c isotype control products

APPLICATION

Application Note

Use at a concentration/dilution equivalent to that of your experimental primary antibody.

Product Note

Unknown

PROPERTIES

Form

Liquid

Buffer

Borate buffered saline

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Negative control , monoclonal Mouse IgG2c isotype control , Mouse IgG2c negative control , Isotype control for Mouse IgG2c , Mouse isotype control for IgG2c , Isotype control to Mouse IgG2c , Mouse IgG2c isotype control , Mouse negative control for IgG2c

Background

Inclusion of an appropriate isotype control is essential for the proper interpretation of experimental results. Because isotype control antibodies have no relevant specificity, they enable the researcher to distinguish non-specific "background" binding from antigen-specific antibody binding. Non-specific binding of primary antibodies may occur due to either binding of antibody to Fc receptors or non-specific interactions with cellular proteins, lipids, or carbohydrates. Additionally, autofluorescence or endogenous enzyme activity in target cells may give a false positive that could be misinterpreted as antibody binding. These factors vary by target cell type and the isotype of the primary antibody. Therefore, the primary antibody used should be matched to an isotype control of identical species and isotype (including both heavy and light chains).

REFERENCE

Application Reference

Lewis PE et al. Vaccines (Basel) 2020; 8 (2) CTLA-4 Blockade, during HIV Virus-Like Particles Immunization, Alters HIV-Specific B-Cell Responses.
Bootz A et al. PLoS Pathog 2017; 13 (8) : e1006601 Protective capacity of neutralizing and non-neutralizing antibodies against glycoprotein B of cytomegalovirus.
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Package List Price ($)
$ 79