GeneTex
United States (US)

Mouse MCP1 / CCL2 protein

Cat No. GTX29901-pro

Species Mouse
PRODUCT

Product Description

Monocyte Chemotactic Protein-1 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 125 amino acids and having a molecular mass of 14 kDa.
APPLICATION

Calculated MW

16.33 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with ddH₂O but not less than 100 μg/ml.

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and avoid freeze-thaw cycles.

Region/Sequence

The sequence of the first five N-terminal amino acids was determined and was found to be Gln-Pro-Asp-Ala-Val.

Expression System

E. coli

Purity

> 99% by SDS-PAGE and HPLC.

Endotoxin

< 1 EU/μg

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

chemokine (C-C motif) ligand 2 , AI323594 , HC11 , JE , MCAF , MCP-1 , MCP1 , SMC-CF , Scya2 , Sigje

Background

This gene is one of several cytokine genes clustered on chromosome 11. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and memory T cells but not for neutrophils. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. [provided by RefSeq, Sep 2015]

Database

Package List Price ($)
$ 299