*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
HeLa , Jurkat , Raji , NCI-H929 , 293T , human Mre11-transfected 293T , PC-12
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.58 mg/ml (Please refer to the vial label for the specific concentration.)
Amino acids 182-582 of Mre11 expressed in E. coli.
Protein G purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Mre11 Homolog, Double Strand Break Repair Nuclease , Atld , Hngs1 , Mre11A , Mre11B , Mre11
Mre11 is an 80 kDa protein that acts as a Mn+2 dependent double stranded DNA 3' to 5' exonuclease and a single stranded DNA endonuclease. It is part of a larger complex with Rad50, p95 (Nibrin) and possibly other associated proteins involved in the nucleolytic end-processing of double strand breaks and telomere maintenance.