APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:1000 |
1:10-1:50 |
1:10-1:50 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
KLH conjugated synthetic peptide between 161-187 amino acids from the Central region of human OPRM1.
Purification
Protein A purified followed by peptide affinity purification
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
LMOR , MOP , MOR , MOR1 , OPRM , OPRM1 , opioid receptor mu 1 , Mu Opioid receptor
Cellular Localization
Cell membrane,Cell projection,Axon,Perikaryon,Dendrite,Endosome,Cytoplasm
Background
This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013]
Database
Research Area
DATA IMAGES
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GTX00782 IHC-P Image
IHC-P analysis of human brain tissue using GTX00782 Mu Opioid receptor antibody.
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GTX00782 WB Image
WB analysis of mouse heart tissue lysate using GTX00782 Mu Opioid receptor antibody. Loading : 35μg/lane
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GTX00782 FACS Image
FACS analysis of K562 cells using GTX00782 Mu Opioid receptor antibody. Bottom histogram : primary antibody Top histogram : Negative control cell (Blank)
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REFERENCE
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REVIEW
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