GeneTex
  • Country / Location Selection

United States (US)

Mxi1 antibody

Anti-Mxi1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33961
Anti-Mxi1 antibody used in Western Blot (WB). GTX33961
Anti-Mxi1 antibody used in Immunohistochemistry (IHC). GTX33961

Cat No. GTX33961

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, IHC

Reactivity

Human
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB WB: 0.2-2.5 μg/ml
IHC-P IHC-P: 2-10 μg/ml
IHC Assay dependent
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

Predict Reactivity

Mouse, Rat, Zebrafish, Yeast, Rabbit, Bovine, Dog, Guinea pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 - 1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MXI1

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

MAX interactor 1, dimerization protein , MAD2 , MXD2 , MXI , bHLHc11

Cellular Localization

Nucleus

Background

Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Mxi1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33961

GTX33961 IHC-P Image

Rabbit Anti-MXI1 Antibody Paraffin Embedded Tissue: Human Lung Cellular Data: Epithelial cells of bronchiole Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X

Anti-Mxi1 antibody used in Western Blot (WB). GTX33961

GTX33961 WB Image

WB Suggested Anti-MXI1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human brain

Anti-Mxi1 antibody used in Immunohistochemistry (IHC). GTX33961

GTX33961 IHC Image

IHC Suggested Anti-MXI1 antibody Titration: 5ug/ ml Positive Control: Lung, respiratory epithelium

REFERENCE

There are currently no references for Mxi1 antibody (GTX33961). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Mxi1 antibody (GTX33961). Be the first to share your experience with this product.