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MyD88 antibody, Internal

Anti-MyD88 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX89605
Anti-MyD88 antibody, Internal used in ELISA (ELISA). GTX89605
Anti-MyD88 antibody, Internal used in Western Blot (WB). GTX89605

Cat No. GTX89605

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA, Sandwich ELISA

Reactivity

Human
Package
100 μg ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.1-0.3μg/ml
IHC-P 4-6μg/ml
ELISA Assay dependent
Sandwich ELISA Assay dependent

Note :

IHC-P
Human Tonsil shows staining of clusters of cells some of which are likely plasma cells.

Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89605-PEP).

Product Note

This antibody is expected to recognize reported isoforms 1, 2 and 3 (NP_001166038.1; NP_002459.2; NP_001166039.1).

Predict Reactivity

Mouse, Rat, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-IKYKAMKKEFP, from the internal region of the protein sequence according to NP_001166038.1; NP_002459.2; NP_001166039.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

MYD88 innate immune signal transduction adaptor , MYD88D

Cellular Localization

Cytoplasm , Nucleus

Background

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Database

Research Area

DATA IMAGES

Anti-MyD88 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX89605

GTX89605 IHC-P Image

IHC-P analysis of human tonsil using GTX89605 MyD88 antibody, Internal.
Antigen retrieval : Tris/EDTA buffer pH 9
Dilution : 4μg/ml

Anti-MyD88 antibody, Internal used in ELISA (ELISA). GTX89605

GTX89605 ELISA Image

ELISA analysis of MyD88 protein using GTX89605 MyD88 antibody, Internal.
Capture : GTX112986 (5μg/ml)
Detection : GTX89605 (5μg/ml)

Anti-MyD88 antibody, Internal used in Western Blot (WB). GTX89605

GTX89605 WB Image

WB analysis of human thymus lysate using GTX89605 MyD88 antibody, Internal.
Dilution : 0.2μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf