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MyD88 antibody

Anti-MyD88 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55716
Anti-MyD88 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55716
Anti-MyD88 antibody used in Western Blot (WB). GTX55716

Cat No. GTX55716

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF

Reactivity

Human, Mouse
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 60-309 of human MyD88 (NP_002459.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

MYD88 innate immune signal transduction adaptor , MYD88D

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Database

Research Area

DATA IMAGES

Anti-MyD88 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55716

GTX55716 ICC/IF Image

ICC/IF analysis of Raw264.7 cells using GTX55716 MyD88 antibody.
Blue : DAPI
Dilution : 1:100

Anti-MyD88 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55716

GTX55716 ICC/IF Image

ICC/IF analysis of Jurkat cells using GTX55716 MyD88 antibody.
Blue : DAPI
Dilution : 1:100

Anti-MyD88 antibody used in Western Blot (WB). GTX55716

GTX55716 WB Image

WB analysis of various sample lysates using GTX55716 MyD88 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf