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Myelin basic protein antibody

Anti-Myelin basic protein antibody used in Immunohistochemistry (IHC). GTX85456
Anti-Myelin basic protein antibody used in Immunohistochemistry (IHC). GTX85456
Anti-Myelin basic protein antibody used in Immunohistochemistry (IHC). GTX85456

Cat. No. GTX85456

Host

 Chicken

Clonality

 Polyclonal

Isotype

 IgY

Application

 WB, ICC/IF, IHC

Reactivity

 Human, Mouse, Rat
Package
50 μg ($399)
See all Myelin basic protein products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000-1:2000
ICC/IF Assay dependent
IHC 1:1000-1:2000
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

100 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Chickens were immunized with a synthetic peptide / keyhole limpet hemocyanin (KLH) conjugate. The peptide corresponded to a region of the MBP gene product shared between the human (NP_002376, NCBI) and mouse (NP_034907, NCBI) sequences.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

myelin basic protein

Background

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Myelin basic protein antibody used in Immunohistochemistry (IHC). GTX85456

GTX85456 IHC Image

IHC analysis of hippocampal region of a transgenic adult mouse brain using GTX85456 Myelin basic protein antibody. This particular transgenic mouse expresses low levels of GFP autofluorescence until control of an actin promoter region.
Red : Primary antibody
Dilution : 1:1000

Anti-Myelin basic protein antibody used in Immunohistochemistry (IHC). GTX85456

GTX85456 IHC Image

IHC analysis of sciatic nerve of an adult rat using GTX85456 Myelin basic protein antibody.
Green : Primary antibody
Red : ubliquitous gene product
Blue : DAPI

Anti-Myelin basic protein antibody used in Immunohistochemistry (IHC). GTX85456

GTX85456 IHC Image

IHC analysis of sciatic nerve of an adult rat using GTX85456 Myelin basic protein antibody.
Green : Primary antibody
Red : ubliquitous gene product
Blue : DAPI

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399