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Myeloperoxidase antibody [MSVA-692M] HistoMAX™

HistoMAX
Anti-Myeloperoxidase antibody [MSVA-692M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04470
Anti-Myeloperoxidase antibody [MSVA-692M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04470
Anti-Myeloperoxidase antibody [MSVA-692M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04470

Cat. No. GTX04470

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MSVA-692M

Isotype

 IgG2a

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($629),
100 μl ($299)
See all Myeloperoxidase products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.
Not tested in other applications.

Calculated MW

84 kDa. ( Note )

Positive Control

Spleen: Numerous granulocytes with strong MPO staining should be seen within the red pulp of the spleen.

Negative Control

Colon: MPO immunostaining should be absent in all epithelial cells of the colon while MPO positive granulocytes may be seen within capillaries or in the stroma of the lamina propria.

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of human MPO protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

myeloperoxidase

Cellular Localization

Lysosome

Background

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]

Database

Research Area

DATA IMAGES

Anti-Myeloperoxidase antibody [MSVA-692M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04470

GTX04470 IHC-P Image

IHC-P analysis of human colon descendens mucosa tissue section using GTX04470 Myeloperoxidase antibody [MSVA-692M] HistoMAX™.
In the normal colon Myeloperoxidase positive granulocytes occur within small capillaries and also the stroma of the lamina propria

Anti-Myeloperoxidase antibody [MSVA-692M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04470

GTX04470 IHC-P Image

IHC-P analysis of human oral squamous cell carcinoma tissue section using GTX04470 Myeloperoxidase antibody [MSVA-692M] HistoMAX™.
Numerous Myeloperoxidase positive intravascular and stromal granulocytes are seen in a squamous cell carcinoma of the oral cavity.

Anti-Myeloperoxidase antibody [MSVA-692M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04470

GTX04470 IHC-P Image

IHC-P analysis of human spleen tissue section using GTX04470 Myeloperoxidase antibody [MSVA-692M] HistoMAX™.
Numerous Myeloperoxidase positive granulocytes are usually seen within the red pulp of the spleen.

REFERENCE

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REVIEW

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Package List Price ($)
$ 629
$ 299