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Myosin 1C antibody

Anti-Myosin 1C antibody used in IHC (Paraffin sections) (IHC-P). GTX55719
Anti-Myosin 1C antibody used in IHC (Paraffin sections) (IHC-P). GTX55719
Anti-Myosin 1C antibody used in Western Blot (WB). GTX55719

Cat. No. GTX55719

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Myosin 1C products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

122 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 769-1028 of human MYO1C (NP_203693.3).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

myosin IC , MMI-beta , MMIb , NMI , myr2

Cellular Localization

Nucleus,Cell membrane,Cytoplasmic vesicle,Nucleolus

Background

This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Myosin 1C antibody used in IHC (Paraffin sections) (IHC-P). GTX55719

GTX55719 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX55719 Myosin 1C antibody.
Dilution : 1:100

Anti-Myosin 1C antibody used in IHC (Paraffin sections) (IHC-P). GTX55719

GTX55719 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX55719 Myosin 1C antibody.
Dilution : 1:100

Anti-Myosin 1C antibody used in Western Blot (WB). GTX55719

GTX55719 WB Image

WB analysis of various lysates using GTX55719 Myosin 1C antibody.
Loading : 25 μg
Dilution : 1:1500

REFERENCE

Application Reference

Tan X et al. Sci Adv 2021; 7 (25) p53 loss activates prometastatic secretory vesicle biogenesis in the Golgi.
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399