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Myosin Heavy Chain 11 antibody [MYH11/2303R]

Anti-Myosin Heavy Chain 11 antibody [MYH11/2303R] used in IHC (Paraffin sections) (IHC-P). GTX02683
Anti-Myosin Heavy Chain 11 antibody [MYH11/2303R] used in IHC (Paraffin sections) (IHC-P). GTX02683
Anti-Myosin Heavy Chain 11 antibody [MYH11/2303R] used in IHC (Paraffin sections) (IHC-P). GTX02683

Cat No. GTX02683

Host

Rabbit

Clonality

Monoclonal

Clone Name

MYH11/2303R

Isotype

IgG

Application

IHC-P

Reactivity

Human, Rat, Rabbit, Bovine, Cat, Dog, Chicken, Guinea pig, Pig
Package
100 μg ($429)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1-2 μg/ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.

Not tested in other applications.

Calculated MW

227 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA, 0.05% azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human MYH11 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

myosin heavy chain 11 , AAT4 , FAA4 , SMHC , SMMHC

Background

The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Myosin Heavy Chain 11 antibody [MYH11/2303R] used in IHC (Paraffin sections) (IHC-P). GTX02683

GTX02683 IHC-P Image

IHC-P analysis of human breast carcinoma section using GTX02683 Myosin Heavy Chain 11 antibody [MYH11/2303R].

Anti-Myosin Heavy Chain 11 antibody [MYH11/2303R] used in IHC (Paraffin sections) (IHC-P). GTX02683

GTX02683 IHC-P Image

IHC-P analysis of human breast carcinoma section using GTX02683 Myosin Heavy Chain 11 antibody [MYH11/2303R].

Anti-Myosin Heavy Chain 11 antibody [MYH11/2303R] used in IHC (Paraffin sections) (IHC-P). GTX02683

GTX02683 IHC-P Image

IHC-P analysis of human prostate carcinoma section using GTX02683 Myosin Heavy Chain 11 antibody [MYH11/2303R].

REFERENCE

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REVIEW

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Package List Price ($)
$ 429