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N-Cadherin antibody

KO/KD Orthogonal
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345
Anti-N-Cadherin antibody used in IHC (Frozen sections) (IHC-Fr). GTX127345
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345
Anti-N-Cadherin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX127345
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345
Anti-N-Cadherin antibody used in IHC (Frozen sections) (IHC-Fr). GTX127345
Anti-N-Cadherin antibody used in IHC (Paraffin sections) (IHC-P). GTX127345
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345

Cat. No. GTX127345

Reference 64
10

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IHC-Fr

Reactivity

 Human, Mouse, Rat, Monkey
Package
100 μl ($399),
25 μl ($169)
See all N-Cadherin products
PRODUCT

Summary

N-Cadherin antibody recognizes N-cadherin protein, a calcium-dependent cell adhesion protein (predicted molecular weight of 100 kDa) encoded by the CDH2 gene. N-cadherin is involved in multiple processes, including neuron development and epithelial-mesenchymal transition (EMT). Due to the prominent role of EMT in cancer progression and metastasis, antibodies targeting either N-cadherin or E-cadherin are frequently used together to study the EMT process: the upregulation of N-cadherin followed by the downregulation of E-cadherin.

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:1000
IHC-P 1:100-1:1000
IHC-Fr 1:100-1:1000
Not tested in other applications.

Calculated MW

100 kDa. ( Note )

Positive Control

NT2D1 , SK-N-SH

Predict Reactivity

Bovine, Dog, Chicken, Xenopus tropicalis(>80% identity)

PROPERTIES

Form

Liquid

Buffer

1XPBS (pH7), 1% BSA, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.15 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human N-Cadherin. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2885644

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cadherin 2 , CD325 , CDHN , CDw325 , NCAD

Cellular Localization

Cell membrane

Background

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345

GTX127345 WB Image

KO/KD

Wild-type (WT) and N-Cadherin knockout (KO) 293T cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with N-Cadherin antibody (GTX127345) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-N-Cadherin antibody used in IHC (Frozen sections) (IHC-Fr). GTX127345

GTX127345 IHC-Fr Image

N-Cadherin antibody detects N-Cadherin protein expression by immunohistochemical analysis.
Sample: Frozen sectioned E13.5 Rat brain.
Green: N-Cadherin protein stained by N-Cadherin antibody (GTX127345) diluted at 1:250.
Red: beta Tubulin 3/ TUJ1, a mature neuron marker, stained by beta Tubulin 3/ TUJ1 antibody [GT11710] (GTX631836) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345

GTX127345 WB Image

Various tissue extracts (50 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with N-Cadherin antibody (GTX127345) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-N-Cadherin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX127345

GTX127345 ICC/IF Image

N-Cadherin antibody detects N-Cadherin protein at cell membrane by immunofluorescent analysis.
Sample: SH-SY5Y cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: N-Cadherin protein stained by N-Cadherin antibody (GTX127345) diluted at 1:500.
Blue: Hoechst 33342 staining.
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345

GTX127345 WB Image

Whole cell extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with N-Cadherin antibody (GTX127345) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-N-Cadherin antibody used in IHC (Frozen sections) (IHC-Fr). GTX127345

GTX127345 IHC-Fr Image

N-Cadherin antibody detects N-Cadherin protein on embryonic mouse brain by immunohistochemical analysis. Sample: Frozen section of embryonic mouse brain (mE18.5). N-Cadherin antibody (GTX127345) diluted at 1:500.

Anti-N-Cadherin antibody used in IHC (Paraffin sections) (IHC-P). GTX127345

GTX127345 IHC-P Image

N-Cadherin antibody detects N-Cadherin protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded mouse liver.
N-Cadherin stained by N-Cadherin antibody (GTX127345) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345

GTX127345 WB Image

Whole cell extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with N-Cadherin antibody (GTX127345) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345

GTX127345 WB Image

Orthogonal

Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with N-Cadherin antibody (GTX127345) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.

REFERENCE

Application Reference

Yin L et al. J Exp Clin Cancer Res 2023; 42 (1) : 204 AR antagonists develop drug resistance through TOMM20 autophagic degradation-promoted transformation to neuroendocrine prostate cancer.
TH Hung et al. Biomed J 2023; : 100612 High expression of embryonic stem cell marker SSEA3 confers poor prognosis and promotes epithelial mesenchymal transition in hepatocellular carcinoma
Application : WB
Reactivity : Human
Chua HH et al. Cell Mol Gastroenterol Hepatol 2023; 15 (1) : 121-152 PIM1-Induced Cytoplasmic Expression of RBMY Mediates Hepatocellular Carcinoma Metastasis.
Application : WB
Reactivity : Human
Chiou HC et al. Antioxidants (Basel) 2023; 12 (2) Copper Exposure Induces Epithelial-Mesenchymal Transition-Related Fibrotic Change via Autophagy and Increase Risk of Lung Fibrosis in Human.
Application : WB
Reactivity : Human
Wang L et al. Bioengineered 2022; 13 (5) : 12941-12954 Stearoyl-CoA desaturase 1 regulates malignant progression of cervical cancer cells.
Show More +
Submit a Reference

REVIEW

N-Cadherin antibody Cat. No. GTX127345

Rating
( Average 4.9 based on 10 users reviews)
Application
Western Blot(WB)
( Average 4.9 based on 10 users reviews)
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345
Date : Anonymous submitted on 24-Jul-2023
Score :
Application Tested : WB
Sample Species : Hu
Figure Note : The data was peer reviewed and published in the 2022 in Front Pharmacol. PMID: 35517780
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345
Date : Anonymous submitted on 24-Jul-2023
Score :
Application Tested : WB
Sample Species : Hu
Figure Note : The data was peer reviewed and published in the 2022 in Front Pharmacol. PMID: 35517780
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345
Date : Anonymous submitted on 24-Jul-2023
Score :
Application Tested : WB
Sample Species : Hu
Figure Note : The data was peer reviewed and published in the 2022 in Front Pharmacol. PMID: 35517780
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345
Date : Anonymous submitted on 24-Jul-2023
Score :
Application Tested : WB
Sample Species : Hu
Figure Note : The data was peer reviewed and published in the 2022 in Front Pharmacol. PMID: 35517780
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345
Date : Anonymous submitted on 18-Mar-2021
Score :
Application Tested : WB
Sample Species : Hu
Figure Note : The data was peer reviewed and published in the journal EMBO Rep in 2020. PMID: 31908141
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345
Date : Anonymous submitted on 18-Mar-2021
Score :
Application Tested : WB
Sample Species : Hu
Figure Note : The data was peer reviewed and published in the journal EMBO Rep in 2020. PMID: 31908141
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345
Date : Anonymous submitted on 18-Mar-2021
Score :
Application Tested : WB
Sample Species : Hu
Figure Note : The data was peer reviewed and published in the journal EMBO Rep in 2020. PMID: 31908141
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345
Date : Anonymous submitted on 26-Nov-2019
Score :
Application Tested : WB
Sample Species : Rat
Sample : Membranes from cortical neurons
Amount used : 50 μg
Blocking : 5% milk, 24°C, 2Hr
Primary Antibody : 1:1000, 4°C, 16Hr
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345
Date : Anonymous submitted on 29-Dec-2017
Score :
Application Tested : WB
Sample Species : Hu
Sample : FaDu xenograft
Amount used : 30 μg
Blocking : 4% non-fat milk in TBST, 23°C, 1Hr
Primary Antibody : 1:2000, 4°C, 16Hr
Anti-N-Cadherin antibody used in Western Blot (WB). GTX127345
Date : Anonymous submitted on 05-Nov-2014
Score :
Application Tested : WB
Sample Species : Hu
Sample : A549 cells
Amount used : 20μg
Blocking : 5% skim milk in TBST, 24°C, 1Hr
Primary Antibody : 1:3000, 24°C, 15Hr
Show More +
Submit a Review
Application Reference
Yin L et al. J Exp Clin Cancer Res 2023; 42 (1):204 AR antagonists develop drug resistance through TOMM20 autophagic degradation-promoted transformation to neuroendocrine prostate cancer.
TH Hung et al. Biomed J 2023;:100612 High expression of embryonic stem cell marker SSEA3 confers poor prognosis and promotes epithelial mesenchymal transition in hepatocellular carcinoma
Application : WB
Reactivity : Human
Chua HH et al. Cell Mol Gastroenterol Hepatol 2023; 15 (1):121-152 PIM1-Induced Cytoplasmic Expression of RBMY Mediates Hepatocellular Carcinoma Metastasis.
Application : WB
Reactivity : Human
Chiou HC et al. Antioxidants (Basel) 2023; 12 (2) Copper Exposure Induces Epithelial-Mesenchymal Transition-Related Fibrotic Change via Autophagy and Increase Risk of Lung Fibrosis in Human.
Application : WB
Reactivity : Human
Kosim MY et al. Front Pharmacol 2022; 13:988335 p53 status modifies cytotoxic activity of lactoferrin under hypoxic conditions.
Application : WB
Reactivity : Human
Chang KS et al. Int J Mol Sci 2022; 23 (19) WNT1 Inducible Signaling Pathway Protein 1 Is a Stroma-Specific Secreting Protein Inducing a Fibroblast Contraction and Carcinoma Cell Growth in the Human Prostate.
Application : WB
Reactivity : Human
Wang L et al. Bioengineered 2022; 13 (5):12941-12954 Stearoyl-CoA desaturase 1 regulates malignant progression of cervical cancer cells.
Huang-Chi Chen et al. Front Pharmacol 2022; 13:877125 Effects of Montelukast on Arsenic-Induced Epithelial-Mesenchymal Transition and the Role of Reactive Oxygen Species Production in Human Bronchial Epithelial Cells.
Application : WB
Reactivity : Human
Zhu X et al. Sci Adv 2022; 8 (9):eabl7263 BRN2 as a key gene drives the early primate telencephalon development.
Application : IHC-Fr
Reactivity : Monkey
Zou W et al. J Cell Mol Med 2022; siRNA-induced CD44 knockdown suppresses the proliferation and invasion of colorectal cancer stem cells through inhibiting epithelial-mesenchymal transition.
Application : WB
Reactivity : Mouse
Lee WJ et al. J Food Drug Anal 2021; 29 (1):113-127 Tea polyphenol epigallocatechin-3-gallate inhibits cell proliferation in a patient-derived triple-negative breast cancer xenograft mouse model via inhibition of proline-dehydrogenase-induced effects.
Mai Takahashi et al. Front Pharmacol 2021; 12:643980 Iron-Dependent Mitochondrial Dysfunction Contributes to the Pathogenesis of Pulmonary Fibrosis.
Application : WB
Reactivity : Human
Lai YW et al. Cells 2021; 10 (8) Prognostic Value of a Glycolytic Signature and Its Regulation by Y-Box-Binding Protein 1 in Triple-Negative Breast Cancer.
Application : WB
Reactivity : Human
Wang LT et al. Cancer Lett 2021; 520:160-171 Phosphorylation of intestine-specific homeobox by ERK1 modulates oncogenic activity and sorafenib resistance.
Application : WB
Reactivity : Mouse
Belvedere R et al. Eur J Pharm Sci 2021; 163:105886 The promising pro-healing role of the association of mesoglycan and lactoferrin on skin lesions.
Milani M et al. J Neuroinflammation 2021; 18 (1):132 Targeting S100A4 with niclosamide attenuates inflammatory and profibrotic pathways in models of amyotrophic lateral sclerosis.
Application : WB
Reactivity : Human
Nicolai A et al. Pharmaceuticals (Basel) 2021; 14 (6) Anti-Tumoral Effects of a (1H-Pyrrol-1-yl)Methyl-1H-Benzoimidazole Carbamate Ester Derivative on Head and Neck Squamous Carcinoma Cell Lines.
Application : WB
Reactivity : Human
Ou M et al. Oncol Rep 2021; 46 (1) MDM2 induces EMT via the B?Raf signaling pathway through 14?3?3.
Application : WB, IHC-P
Reactivity : Human
Li Y et al. Transl Lung Cancer Res 2021; 10 (4):1841-1856 Let-7b-3p inhibits tumor growth and metastasis by targeting the BRF2-mediated MAPK/ERK pathway in human lung adenocarcinoma.
Application : WB
Reactivity : Human
Milani M et al. Research Square 2021; (Epub) Niclosamide Targets Inammatory and Probrotic Pathways in Amyotrophic Lateral Sclerosis.
Application : WB
Hu W et al. JCI Insight 2021; 6 (3) NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma.
Application : WB
Reactivity : Mouse
Chen YT et al. J Clin Invest 2021; 131 (5) Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts.
Application : WB
Reactivity : Mouse
Chen H.Y. et al. Cancers 2021; 13 (6):1236 Isoliquiritigenin Reverses Epithelial-Mesenchymal Transition Through Modulation of the TGF-β/Smad Signaling Pathway in Endometrial Cancer.
Application : WB, ICC/IF
Reactivity : Human
Duan C et al. Oncol Lett 2021; 21 (2):143 L-fucose ameliorates the carcinogenic properties of Fusobacterium nucleatum in colorectal cancer.
Application : WB
Reactivity : Human
Russell DF et al. Front Neuroanat 2020; 14:50 Large-Scale Convergence of Receptor Cell Arrays Onto Afferent Terminal Arbors in the Lorenzinian Electroreceptors of Polyodon.
Kuo TT et al. ACS Omega 2020; 5 (49):31792-31800 Melissa officinalis Extract Induces Apoptosis and Inhibits Migration in Human Colorectal Cancer Cells.
Application : WB
Reactivity : Human
Kuo CH et al. Cell Biochem Funct 2020; (Epub) Biomarker discovery in highly invasive lung cancer cell through proteomics approaches.
Application : WB
Reactivity : Human
Krzysiek-Maczka G et al. Microorganisms 2020; 8 (10) Long-Term Helicobacter pylori Infection Switches Gastric Epithelium Reprogramming Towards Cancer Stem Cell-Related Differentiation Program in Hp-Activated Gastric Fibroblast-TGFβ Dependent Manner.
Application : WB
Reactivity : Rat
Ho KH et al. Cell Mol Neurobiol 2020; miR-4286 is Involved in Connections Between IGF-1 and TGF-β Signaling for the Mesenchymal Transition and Invasion by Glioblastomas.
Application : WB
Reactivity : Human
Wang LT et al. EMBO Rep 2020; 21 (2):e48795 PCAF-mediated acetylation of ISX recruits BRD4 to promote epithelial-mesenchymal transition.
Lee JY et al. PLoS One 2020; 15 (7):e0236876 PHRF1 promotes migration and invasion by modulating ZEB1 expression.
Application : WB
Reactivity : Human
Wang SC et al. Biochem Pharmacol 2020; 180:114152 α-Linolenic acid inhibits the migration of human triple-negative breast cancer cells by attenuating Twist1 expression and suppressing Twist1-mediated epithelial-mesenchymal transition.
Application : WB
Reactivity : Human
Li Z et al. Front Cell Neurosci 2020; 14:144 MicroRNA-124 Overexpression in Schwann Cells Promotes Schwann Cell-Astrocyte Integration and Inhibits Glial Scar Formation Ability.
Application : WB
Reactivity : Rat
Le Saux G et al. ACS Appl Mater Interfaces 2020; 12 (20):22399-22409 Cell-Cell Adhesion-Driven Contact Guidance and Its Effect on Human Mesenchymal Stem Cell Differentiation.
Reactivity : Human
Fang CH et al. J Biomed Sci 2020; 27 (1):42 A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and 帣-catenin-ABCG2 signaling.
Application : WB
Reactivity : Human
Yang P et al. Exp Biol Med (Maywood) 2019; 244 (18):1608-1618 ResolvinD1 attenuates high-mobility group box 1-induced epithelial-to-mesenchymal transition in nasopharyngeal carcinoma cells.
Yang P et al. Int J Med Sci 2019; 16 (12):1631-1641 Agonist of PPAR-γ Reduced Epithelial-Mesenchymal Transition in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps via Inhibition of High Mobility Group Box1.
Marcinkiewcz CA et al. ACS Chem Neurosci 2019; 10 (7):3154-3166 Sex-Dependent Modulation of Anxiety and Fear by 5-HT1A Receptors in the Bed Nucleus of the Stria Terminalis.
Raineri A et al. Int J Mol Sci 2019; 20 (23) Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability.
Hsu SY et al. Onco Targets Ther 2019; 12:7611-7621 A novel CXCL8 analog is effective in inhibiting the growth via cell cycle arrest and attenuating invasion of Lewis lung carcinoma.
Application : WB
Reactivity : Mouse
Li-Chien Chang et al. Nutrition 2019; (Epub) 1,25(OH)2D3 attenuates indoxyl sulfate-induced epithelial-to-mesenchymal cell transition via inactivation of PI3K/Akt/?]-catenin signaling in renal tubular epithelial cells.
Kuo YL et al. Sci Rep 2019; 9 (1):10269 Hypoxia-induced epithelial-mesenchymal transition and fibrosis for the development of breast capsular contracture.
Application : WB
Reactivity : Mouse
Hung CY et al. Mol Neurobiol 2019; Sp1 in Astrocyte Is Important for Neurite Outgrowth and Synaptogenesis.
Application : WB
Reactivity : Mouse
Lee DK et al. Biochem Biophys Res Commun 2019; 514 (3):645-652 Cdk5 regulates N-cadherin-dependent neuronal migration during cortical development.
Reactivity : Mouse
Pei YF et al. Am J Pathol 2019; (Epub) Methyl-CpG Binding Domain Protein 2 Inhibits the Malignant Characteristic of Lung Adenocarcinoma through the Epigenetic Modulation of 10 to 11 Translocation 1 and miR-200s.
Application : WB
Reactivity : Human
Mansel C et al. Neurotoxicol Teratol 2019; 72:58-70 Lead exposure reduces survival, neuronal determination, and differentiation of P19 stem cells.
Application : ICC/IF
Reactivity : Mouse
Chang CY et al. Cell Death Discov 2018; 4:100 PEGylated liposome-encapsulated rhenium-188 radiopharmaceutical inhibits proliferation and epithelial-mesenchymal transition of human head and neck cancer cells in vivo with repeated therapy.
Application : WB
Reactivity : Mouse
DaSilva-Arnold S et al. Mol Hum Reprod 2018; (Epub) heZEB2, a master regulator of the epithelial-mesenchymal transition, mediates trophoblast differentiation.
Application : WB
Reactivity : Human
Chen CM et al. J Renin Angiotensin Aldosterone Syst 2018; 19 (3):1.47E+15 Hyperglycemia activates the renin-angiotensin system and induces epithelial-mesenchymal transition in streptozotocin-induced diabetic kidneys.
Application : IHC-P
Li JM et al. Ther Adv Med Oncol 2018; 10:1.76E+15 Upregulation of LGALS1 is associated with oral cancer metastasis.
Application : WB
Reactivity : Human
Hseu YC et al. J Cell Physiol 2018; 234 (4):4125-4139 Antrodia camphorata inhibits epithelial-to-mesenchymal transition by targeting multiple pathways in triple-negative breast cancers.
Application : WB
Reactivity : Human
Terasaki M et al. Anticancer Res 2018; 38 (4):2169-2179 Glycine Is a Predictor for a Suppressive Effect of Fucoxanthinol on Colonosphere Formation Under Hypoxia.
Application : WB
Reactivity : Human
Chen CY et al. Int J Mol Sci 2018; 19 (2) Corylin Suppresses Hepatocellular Carcinoma Progression via the Inhibition of Epithelial-Mesenchymal Transition, Mediated by Long Noncoding RNA GAS5.
Application : WB
Reactivity : Human
Shentu TP et al. Sci Rep 2017; 7 (1):18052 Thy-1 dependent uptake of mesenchymal stem cell-derived extracellular vesicles blocks myofibroblastic differentiation.
Application : WB
Reactivity : Human
Chen PC et al. J Cell Physiol 2017; (Epub) Activation of Fibroblasts by Nicotine Promotes the Epithelial-Mesenchymal Transition and Motility of Breast Cancer Cells.
Application : WB
Reactivity : Human
Taglieri L et al. Invest New Drugs 2017; (Epub) The kinesin Eg5 inhibitor K858 induces apoptosis and reverses the malignant invasive phenotype in human glioblastoma cells.
Application : WB
Reactivity : Human
Chou HC et al. Toxicological Sciences 2017; (Epub) L-carnitine via PPARγ- and Sirt1-dependent mechanisms attenuates epithelial–mesenchymal transition and renal fibrosis caused by perfluorooctanesulfonate.
Application : WB
Chan SM et al. Sci Rep 2017; 7 (1):8646 Levobuipivacaine-Induced Dissemination of A549 Lung Cancer Cells.
Application : WB
Reactivity : Human
Fujiki K et al. J Biol Chem 2017; (Epub) Involvement of Notch1 signaling in malignant progression of A549 cells subjected to prolonged cadmium exposure.
Application : WB
Reactivity : Human
Tong D et al. Cancer Lett 2016; 389:23-32 * inhibits castration-induced emt in prostate cancer by repressing cox2/pge2/stat3 axis.
Application : WB, IHC-P
Reactivity : Human
Jian MY et al. Am J Physiol Lung Cell Mol Physiol 2016; 310 (1):L71-85 N-cadherin coordinates AMP kinase-mediated lung vascular repair.
Application : WB
Reactivity : Rat
Li CH et al. Arch Toxicol 2016; (Epub) Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial-mesenchymal transition in non-small cell lung cancer cells.
Application : WB
Reactivity : Human
Jheng HF et al. Mol Nutr Food Res 2016; (Epub) Dietary low-fat soy milk powder retards diabetic nephropathy progression via inhibition of renal fibrosis and renal inflammation.
Application : IHC-P
Reactivity : Mouse
Chen LH et al. BMC Cancer 2016; 16:431 Involvement of DNMT 3B promotes epithelial-mesenchymal transition and gene expression profile of invasive head and neck squamous cell carcinomas cell lines.
Application : WB
Reactivity : Human
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