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United States (US)

NAGK antibody

Cat. No. GTX116238

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF, PLA

Reactivity

 Rat
Package
100 μl ($399),
25 μl ($169)
See all NAGK products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
PLA Assay dependent
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

Predict Reactivity

Human, Mouse, Bovine(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human NAGK. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_11171367

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

N-acetylglucosamine kinase , GNK , HSA242910

Background

N-acetylglucosamine kinase (NAGK; EC 2.7.1.59) converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. NAGK belongs to the group of N-acetylhexosamine kinases and is a prominent salvage enzyme of amino sugar metabolism in mammals.[supplied by OMIM]

Database

Research Area

REFERENCE

Application Reference

Sharif SR et al. Mol Cells 2015; 38 (5) : 402-8 N-acetyl-D-glucosamine kinase is a component of nuclear speckles and paraspeckles.
Application : ICC/IF, PLA
Reactivity : Rat
Islam MA et al. Mol Cells 2015; 38 (10) : 876-85 N-Acetyl-D-Glucosamine Kinase Promotes the Axonal Growth of Developing Neurons.
Application : ICC/IF, PLA
Reactivity : Rat
Islam MA et al. Exp Mol Med 2015; 47 : e177 N-acetyl-D-glucosamine kinase interacts with dynein light-chain roadblock type 1 at Golgi outposts in neuronal dendritic branch points.
Application : ICC/IF, PLA
Reactivity : Rat
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169